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Epstein Barr-Virus Latent Membrane Protein-2A-Induced ΔNp63α Expression is Associated with Impaired Epithelial Cell Differentiation

Epstein-Barr virus (EBV) is an oncogenic γ-herpes virus associated with malignancies that develop in both lymphoid and epithelial cells including nasopharyngeal carcinoma (NPC). The EBV protein latent membrane protein 2A (LMP2A) is expressed in NPC and can modulate epithelial proliferation, transfor...

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Detalles Bibliográficos
Autores principales: Fotheringham, Julie A., Mazzucca, Stephanie, Raab-Traub, Nancy
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912443/
https://www.ncbi.nlm.nih.gov/pubmed/20498633
http://dx.doi.org/10.1038/onc.2010.175