Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)

Poly(ADP-ribosyl)ation represents an important post-translational modification in higher eukaryotes. Several DNA repair/checkpoint proteins possess specific PAR-Binding Zinc finger (PBZ) modules critical for function. Here, we present solution structures of the two PBZ modules of APLF (Aprataxin and...

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Detalles Bibliográficos
Autores principales: Eustermann, Sebastian, Brockmann, Christoph, Mehrotra, Pawan Vinod, Yang, Ji-Chun, Loakes, David, West, Stephen C., Ahel, Ivan, Neuhaus, David
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912505/
https://www.ncbi.nlm.nih.gov/pubmed/20098424
http://dx.doi.org/10.1038/nsmb.1747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912505/
https://www.ncbi.nlm.nih.gov/pubmed/20098424
http://dx.doi.org/10.1038/nsmb.1747

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