The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

The swine-origin H1N1 influenza A virus emerged in early 2009 and caused the first influenza pandemic in 41 years. The virus has spread efficiently to both the Northern and the Southern Hemispheres and has been associated with over 16,000 deaths. Given the virus’s recent zoonotic origin, there is co...

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Detalles Bibliográficos
Autores principales: Jagger, Brett W., Memoli, Matthew J., Sheng, Zong-Mei, Qi, Li, Hrabal, Rachel J., Allen, Genevieve L., Dugan, Vivien G., Wang, Ruixue, Digard, Paul, Kash, John C., Taubenberger, Jeffery K.
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912665/
https://www.ncbi.nlm.nih.gov/pubmed/20689744
http://dx.doi.org/10.1128/mBio.00067-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912665/
https://www.ncbi.nlm.nih.gov/pubmed/20689744
http://dx.doi.org/10.1128/mBio.00067-10

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