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The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase
The swine-origin H1N1 influenza A virus emerged in early 2009 and caused the first influenza pandemic in 41 years. The virus has spread efficiently to both the Northern and the Southern Hemispheres and has been associated with over 16,000 deaths. Given the virus’s recent zoonotic origin, there is co...
Autores principales: | Jagger, Brett W., Memoli, Matthew J., Sheng, Zong-Mei, Qi, Li, Hrabal, Rachel J., Allen, Genevieve L., Dugan, Vivien G., Wang, Ruixue, Digard, Paul, Kash, John C., Taubenberger, Jeffery K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912665/ https://www.ncbi.nlm.nih.gov/pubmed/20689744 http://dx.doi.org/10.1128/mBio.00067-10 |
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