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Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Wang, Ping, Ye, Zhi-Qiang, Xu, Heng, He, Zhisong, Feng, Kai-Yan, Hu, LeLe, Cui, WeiRen, Wang, Kai, Dong, Xiao, Xie, Lu, Kong, Xiangyin, Cai, Yu-Dong, Li, Yixue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912763/
https://www.ncbi.nlm.nih.gov/pubmed/20689580
http://dx.doi.org/10.1371/journal.pone.0011900