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Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties
Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912763/ https://www.ncbi.nlm.nih.gov/pubmed/20689580 http://dx.doi.org/10.1371/journal.pone.0011900 |