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Correcting the Bias of Empirical Frequency Parameter Estimators in Codon Models

Markov models of codon substitution are powerful inferential tools for studying biological processes such as natural selection and preferences in amino acid substitution. The equilibrium character distributions of these models are almost always estimated using nucleotide frequencies observed in a se...

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Detalles Bibliográficos
Autores principales: Kosakovsky Pond, Sergei, Delport, Wayne, Muse, Spencer V., Scheffler, Konrad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912764/
https://www.ncbi.nlm.nih.gov/pubmed/20689581
http://dx.doi.org/10.1371/journal.pone.0011230