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Molecular Evolution of the Primate Antiviral Restriction Factor Tetherin
BACKGROUND: Tetherin is a recently identified antiviral restriction factor that restricts HIV-1 particle release in the absence of the HIV-1 viral protein U (Vpu). It is reminiscent of APOBEC3G and TRIM5a that also antagonize HIV. APOBEC3G and TRIM5a have been demonstrated to evolve under pervasive...
Autores principales: | Liu, Jun, Chen, Keping, Wang, Jian-Hua, Zhang, Chiyu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912774/ https://www.ncbi.nlm.nih.gov/pubmed/20689591 http://dx.doi.org/10.1371/journal.pone.0011904 |
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