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CD25 Appears Non Essential for Human Peripheral T(reg) Maintenance In Vivo

BACKGROUND: IL-2 has been reported to be critical for peripheral T(reg) survival in mouse models. Here, we examined T(reg) maintenance in a series of paediatric liver transplant recipients who received basiliximab, a therapeutic anti-CD25 monoclonal antibody. METHODOLOGY/PRINCIPAL FINDINGS: FoxP3(+)...

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Detalles Bibliográficos
Autores principales: de Goër de Herve, Marie-Ghislaine, Gonzales, Emmanuel, Hendel-Chavez, Houria, Décline, Jean-Luc, Mourier, Olivia, Abbed, Karim, Jacquemin, Emmanuel, Taoufik, Yassine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912775/
https://www.ncbi.nlm.nih.gov/pubmed/20689592
http://dx.doi.org/10.1371/journal.pone.0011784