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Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy
BACKGROUND: The administration of rituximab (RTX) in vivo results in B-cell depletion, but evidence for multiple mechanisms of action have been reported. Surprisingly, B cell depletion produced a response in patients with polymyositis, which is characterized as a T cell-mediated autoimmune disorder...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912795/ https://www.ncbi.nlm.nih.gov/pubmed/20618995 http://dx.doi.org/10.1186/1471-2474-11-157 |