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Pneumocystis cell wall β-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells

BACKGROUND: Respiratory failure secondary to alveolar inflammation during Pneumocystis pneumonia is a major cause of death in immunocompromised patients. Neutrophil infiltration in the lung of patients with Pneumocystis infection predicts severity of the infection and death. Several previous studies...

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Detalles Bibliográficos
Autores principales: Carmona, Eva M, Lamont, Jeffrey D, Xue, Ailing, Wylam, Mark, Limper, Andrew H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912823/
https://www.ncbi.nlm.nih.gov/pubmed/20626862
http://dx.doi.org/10.1186/1465-9921-11-95