EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis

BACKGROUND: Proteolytic cleavage of the extracellular domain (EpEx) of Epithelial cell adhesion molecule (EpCAM) and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer cells. The clinical significance of Ep-ICD in human tu...

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Detalles Bibliográficos
Autores principales: Ralhan, Ranju, Cao, Jun, Lim, Terence, MacMillan, Christina, Freeman, Jeremy L, Walfish, Paul G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912862/
https://www.ncbi.nlm.nih.gov/pubmed/20579375
http://dx.doi.org/10.1186/1471-2407-10-331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912862/
https://www.ncbi.nlm.nih.gov/pubmed/20579375
http://dx.doi.org/10.1186/1471-2407-10-331

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