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EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis
BACKGROUND: Proteolytic cleavage of the extracellular domain (EpEx) of Epithelial cell adhesion molecule (EpCAM) and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer cells. The clinical significance of Ep-ICD in human tu...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912862/ https://www.ncbi.nlm.nih.gov/pubmed/20579375 http://dx.doi.org/10.1186/1471-2407-10-331 |