Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule

BACKGROUND: Different isoforms of Cytochrome P450 (CYP) metabolized different types of substrates (or drugs molecule) and make them soluble during biotransformation. Therefore, fate of any drug molecule depends on how they are treated or metabolized by CYP isoform. There is a need to develop models...

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Detalles Bibliográficos
Autores principales: Mishra, Nitish K, Agarwal, Sandhya, Raghava, Gajendra PS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912882/
https://www.ncbi.nlm.nih.gov/pubmed/20637097
http://dx.doi.org/10.1186/1471-2210-10-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912882/
https://www.ncbi.nlm.nih.gov/pubmed/20637097
http://dx.doi.org/10.1186/1471-2210-10-8

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