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Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule
BACKGROUND: Different isoforms of Cytochrome P450 (CYP) metabolized different types of substrates (or drugs molecule) and make them soluble during biotransformation. Therefore, fate of any drug molecule depends on how they are treated or metabolized by CYP isoform. There is a need to develop models...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912882/ https://www.ncbi.nlm.nih.gov/pubmed/20637097 http://dx.doi.org/10.1186/1471-2210-10-8 |