Different integration site structures between L1 protein-mediated retrotransposition in cis and retrotransposition in trans

BACKGROUND: Long interspersed nuclear element-1 (LINE-1 or L1) is a dominant repetitive sequence in the human genome. Besides mediating its own retrotransposition, L1 can mobilize Alu and messenger RNA (mRNA) in trans, and probably also SVA and non-coding RNA. The structures of L1 copies and trans-m...

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Detalles Bibliográficos
Autor principal: Kojima, Kenji K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912911/
https://www.ncbi.nlm.nih.gov/pubmed/20615209
http://dx.doi.org/10.1186/1759-8753-1-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912911/
https://www.ncbi.nlm.nih.gov/pubmed/20615209
http://dx.doi.org/10.1186/1759-8753-1-17

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