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Breath Formate Is a Marker of Airway S-Nitrosothiol Depletion in Severe Asthma

BACKGROUND: Children with severe asthma have poor symptom control and elevated markers of airway oxidative and nitrosative stress. Paradoxically, they have decreased airway levels of S-nitrosothiols (SNOs), a class of endogenous airway smooth muscle relaxants. This deficiency results from increased...

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Detalles Bibliográficos
Autores principales: Greenwald, Roby, Fitzpatrick, Anne M., Gaston, Benjamin, Marozkina, Nadzeya V., Erzurum, Serpil, Teague, W. Gerald
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912922/
https://www.ncbi.nlm.nih.gov/pubmed/20689836
http://dx.doi.org/10.1371/journal.pone.0011919