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Breath Formate Is a Marker of Airway S-Nitrosothiol Depletion in Severe Asthma
BACKGROUND: Children with severe asthma have poor symptom control and elevated markers of airway oxidative and nitrosative stress. Paradoxically, they have decreased airway levels of S-nitrosothiols (SNOs), a class of endogenous airway smooth muscle relaxants. This deficiency results from increased...
Autores principales: | Greenwald, Roby, Fitzpatrick, Anne M., Gaston, Benjamin, Marozkina, Nadzeya V., Erzurum, Serpil, Teague, W. Gerald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912922/ https://www.ncbi.nlm.nih.gov/pubmed/20689836 http://dx.doi.org/10.1371/journal.pone.0011919 |
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