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Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast

PURPOSE: The primary objective of the studies was to demonstrate bioequivalence between the oral granules formulation and chewable tablet of montelukast in the fasted state. Effect of food on the pharmacokinetics of the oral granules was also evaluated. METHODS: The Formulation Biocomparison Study (...

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Detalles Bibliográficos
Autores principales: Knorr, Barbara, Hartford, Alan, Li, Xiujiang (Susie), Yang, Amy Yifan, Noonan, Gertrude, Migoya, Elizabeth
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913109/
https://www.ncbi.nlm.nih.gov/pubmed/20686624
http://dx.doi.org/10.1111/j.1753-5174.2010.00029.x