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Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication

The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect viral replication. However, inhibition of the sterol pathway with statin drugs has not yielded consistent results in patients. Here, we pres...

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Detalles Bibliográficos
Autores principales: Owens, Christopher M, Mawhinney, Christina, Grenier, Jill M, Altmeyer, Ralf, Lee, Margaret S, Borisy, Alexis A, Lehár, Joseph, Johansen, Lisa M
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913396/
https://www.ncbi.nlm.nih.gov/pubmed/20531405
http://dx.doi.org/10.1038/msb.2010.32