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Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication
The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect viral replication. However, inhibition of the sterol pathway with statin drugs has not yielded consistent results in patients. Here, we pres...
Autores principales: | Owens, Christopher M, Mawhinney, Christina, Grenier, Jill M, Altmeyer, Ralf, Lee, Margaret S, Borisy, Alexis A, Lehár, Joseph, Johansen, Lisa M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913396/ https://www.ncbi.nlm.nih.gov/pubmed/20531405 http://dx.doi.org/10.1038/msb.2010.32 |
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