Stress-specific response of the p53-Mdm2 feedback loop

BACKGROUND: The p53 signalling pathway has hundreds of inputs and outputs. It can trigger cellular senescence, cell-cycle arrest and apoptosis in response to diverse stress conditions, including DNA damage, hypoxia and nutrient deprivation. Signals from all these inputs are channeled through a singl...

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Detalles Bibliográficos
Autores principales: Hunziker, Alexander, Jensen, Mogens H, Krishna, Sandeep
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913930/
https://www.ncbi.nlm.nih.gov/pubmed/20624280
http://dx.doi.org/10.1186/1752-0509-4-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913930/
https://www.ncbi.nlm.nih.gov/pubmed/20624280
http://dx.doi.org/10.1186/1752-0509-4-94

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