Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

BACKGROUND: Activation of the extrinsic apoptosis pathway by tumour necrosis factor related apoptosis inducing ligand (TRAIL) is a novel therapeutic strategy for treating cancer that is currently under clinical evaluation. Identification of molecular biomarkers of resistance is likely to play an imp...

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Detalles Bibliográficos
Autores principales: Chacko, Alex D, Liberante, Fabio, Paul, Ian, Longley, Daniel B, Fennell, Dean A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913963/
https://www.ncbi.nlm.nih.gov/pubmed/20646307
http://dx.doi.org/10.1186/1471-2407-10-380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913963/
https://www.ncbi.nlm.nih.gov/pubmed/20646307
http://dx.doi.org/10.1186/1471-2407-10-380

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