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Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

BACKGROUND: Activation of the extrinsic apoptosis pathway by tumour necrosis factor related apoptosis inducing ligand (TRAIL) is a novel therapeutic strategy for treating cancer that is currently under clinical evaluation. Identification of molecular biomarkers of resistance is likely to play an imp...

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Detalles Bibliográficos
Autores principales:	Chacko, Alex D, Liberante, Fabio, Paul, Ian, Longley, Daniel B, Fennell, Dean A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913963/ https://www.ncbi.nlm.nih.gov/pubmed/20646307 http://dx.doi.org/10.1186/1471-2407-10-380

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