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Altered placental expression of PAPPA2 does not affect birth weight in mice

BACKGROUND: Pregnancy-associated plasma protein A2 (PAPPA2) is an insulin-like growth factor binding protein (IGFBP) protease expressed in the placenta and upregulated in pregnancies complicated by pre-eclampsia. The mechanism linking PAPPA2 expression and pre-eclampsia and the consequences of alter...

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Detalles Bibliográficos
Autores principales: Wagner, Pamela K, Christians, Julian K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913990/
https://www.ncbi.nlm.nih.gov/pubmed/20642865
http://dx.doi.org/10.1186/1477-7827-8-90