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UHRF1 is a genome caretaker that facilitates the DNA damage response to γ-irradiation

BACKGROUND: DNA double-strand breaks (DSBs) caused by ionizing radiation or by the stalling of DNA replication forks are among the most deleterious forms of DNA damage. The ability of cells to recognize and repair DSBs requires post-translational modifications to histones and other proteins that fac...

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Detalles Bibliográficos
Autores principales: Mistry, Helena, Tamblyn, Laura, Butt, Hussein, Sisgoreo, Daniel, Gracias, Aileen, Larin, Meghan, Gopalakrishnan, Kalpana, Hande, Manoor Prakash, McPherson, John Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914011/
https://www.ncbi.nlm.nih.gov/pubmed/20678257
http://dx.doi.org/10.1186/2041-9414-1-7