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UHRF1 is a genome caretaker that facilitates the DNA damage response to γ-irradiation
BACKGROUND: DNA double-strand breaks (DSBs) caused by ionizing radiation or by the stalling of DNA replication forks are among the most deleterious forms of DNA damage. The ability of cells to recognize and repair DSBs requires post-translational modifications to histones and other proteins that fac...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914011/ https://www.ncbi.nlm.nih.gov/pubmed/20678257 http://dx.doi.org/10.1186/2041-9414-1-7 |