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Nonconventional Initiation Complex Assembly by STAT and NF-κB Transcription Factors Regulates Nitric Oxide Synthase Expression

Transcriptional regulation of the Nos2 gene encoding inducible nitric oxide synthase (iNOS) requires type I interferon (IFN-I) signaling and additional signals emanating from pattern recognition receptors. Here we showed sequential and cooperative contributions of the transcription factors ISGF3 (a...

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Detalles Bibliográficos
Autores principales: Farlik, Matthias, Reutterer, Benjamin, Schindler, Christian, Greten, Florian, Vogl, Claus, Müller, Mathias, Decker, Thomas
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914224/
https://www.ncbi.nlm.nih.gov/pubmed/20637660
http://dx.doi.org/10.1016/j.immuni.2010.07.001