The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by increased type I interferons (IFNs) and multiorgan inflammation frequently targeting the skin. IFN-kappa is a type I IFN expressed in skin. A pooled genome-wide scan implicated the IFNK locus in SLE susceptibility....

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Detalles Bibliográficos
Autores principales: Harley, Isaac T. W., Niewold, Timothy B., Stormont, Rebecca M., Kaufman, Kenneth M., Glenn, Stuart B., Franek, Beverly S., Kelly, Jennifer A., Kilpatrick, Jeffrey R., Hutchings, David, Divers, Jasmin, Bruner, Gail R., Edberg, Jeffrey C., McGwin, Gerald, Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá-Pérez, Luis M., Merrill, Joan T., Gilkeson, Gary S., Vyse, Timothy J., Alarcón-Riquelme, Marta E., Cho, Soo-Kyung, Jacob, Chaim O., Alarcón, Graciela S., Moser, Kathy L., Gaffney, Patrick M., Kimberly, Robert P., Bae, Sang-Cheol, Langefeld, Carl D., Harley, John B., Guthridge, Joel M., James, Judith A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914299/
https://www.ncbi.nlm.nih.gov/pubmed/20706608
http://dx.doi.org/10.1155/2010/706825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914299/
https://www.ncbi.nlm.nih.gov/pubmed/20706608
http://dx.doi.org/10.1155/2010/706825

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