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Optimal Fluxes, Reaction Replaceability, and Response to Enzymopathies in the Human Red Blood Cell

Characterizing the capabilities, key dependencies, and response to perturbations of genome-scale metabolic networks is a basic problem with important applications. A key question concerns the identification of the potentially most harmful reaction knockouts. The integration of combinatorial methods...

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Detalles Bibliográficos
Autores principales: De Martino, A., Granata, D., Marinari, E., Martelli, C., Van Kerrebroeck, V.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914339/
https://www.ncbi.nlm.nih.gov/pubmed/20706609
http://dx.doi.org/10.1155/2010/415148