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Dual Effect of Neutrophils on pIgR/Secretory Component in Human Bronchial Epithelial Cells: Role of TGF-β

Neutrophils have a dual affect on epithelial pIgR/SC, the critical receptor for transcellular routing of mucosal IgA, but mechanisms of pIgR/SC upregulation remain elusive. Requirements of cytokine, redox, and signalling pathways for pIgR/SC production were assessed in human bronchial epithelial (Ca...

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Detalles Bibliográficos
Autores principales: Ratajczak, Céline, Guisset, Amélie, Detry, Bruno, Sibille, Yves, Pilette, Charles
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914448/
https://www.ncbi.nlm.nih.gov/pubmed/20706611
http://dx.doi.org/10.1155/2010/428618