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A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice

BACKGROUND: Since its first appearance in the USA in 1999, West Nile virus (WNV) has spread in the Western hemisphere and continues to represent an important public health concern. In the absence of effective treatment, there is a medical need for the development of a safe and efficient vaccine. Liv...

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Detalles Bibliográficos
Autores principales: Spohn, Gunther, Jennings, Gary T, Martina, Byron EE, Keller, Iris, Beck, Markus, Pumpens, Paul, Osterhaus, Albert DME, Bachmann, Martin F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914671/
https://www.ncbi.nlm.nih.gov/pubmed/20604940
http://dx.doi.org/10.1186/1743-422X-7-146