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MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

BACKGROUND: MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle progression via direct targeting of p27 and p57 in various human malignancies. How...

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Detalles Bibliográficos
Autores principales: Chun-zhi, Zhang, Lei, Han, An-ling, Zhang, Yan-chao, Fu, Xiao, Yue, Guang-xiu, Wang, Zhi-fan, Jia, Pei-yu, Pu, Qing-yu, Zhang, Chun-sheng, Kang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914702/
https://www.ncbi.nlm.nih.gov/pubmed/20618998
http://dx.doi.org/10.1186/1471-2407-10-367