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Trichomonas Transmembrane Cyclases Result from Massive Gene Duplication and Concomitant Development of Pseudogenes

BACKGROUND: Trichomonas vaginalis has an unusually large genome (∼160 Mb) encoding ∼60,000 proteins. With the goal of beginning to understand why some Trichomonas genes are present in so many copies, we characterized here a family of ∼123 Trichomonas genes that encode transmembrane adenylyl cyclases...

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Detalles Bibliográficos
Autores principales: Cui, Jike, Das, Suchismita, Smith, Temple F., Samuelson, John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914791/
https://www.ncbi.nlm.nih.gov/pubmed/20689771
http://dx.doi.org/10.1371/journal.pntd.0000782