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CELL-BASED OSTEOPROTEGERIN THERAPY FOR DEBRIS-INDUCED ASEPTIC PROSTHETIC LOOSENING ON A MURINE MODEL
Exogenous OPG gene modification appears a therapeutic strategy for osteolytic aseptic loosening. The feasibility and efficacy of a cell-based OPG gene delivery approach were investigated using a murine model of knee prosthesis failure. A titanium pin was implanted into mouse proximal tibia to mimic...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914841/ https://www.ncbi.nlm.nih.gov/pubmed/20428210 http://dx.doi.org/10.1038/gt.2010.64 |