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Synthesis of a pH-Sensitive Nitrilotriacetic Linker to Peptide Transduction Domains To Enable Intracellular Delivery of Histidine Imidazole Ring-Containing Macromolecules

[Image: see text] Intracellular delivery of functional macromolecules using peptide transduction domains (PTDs) is an exciting technology with both experimental and therapeutic applications. Recent data indicate that PTD-mediated transduction occurs via fluid-phase macropinocytosis involving an intr...

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Detalles Bibliográficos
Autores principales: June, Ronald K., Gogoi, Khirud, Eguchi, Akiko, Cui, Xian-Shu, Dowdy, Steven F.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915637/
https://www.ncbi.nlm.nih.gov/pubmed/20681698
http://dx.doi.org/10.1021/ja1040418