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Effect of Microwave Radiation on Enzymatic and Chemical Peptide Bond Synthesis on Solid Phase

Peptide bond synthesis was performed on PEGA beads under microwave radiations. Classical chemical coupling as well as thermolysin catalyzed synthesis was studied, and the effect of microwave radiations on reaction kinetics, beads' integrity, and enzyme activity was assessed. Results demonstrate...

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Detalles Bibliográficos
Autores principales: Basso, Alessandra, Sinigoi, Loris, Gardossi, Lucia, Flitsch, Sabine
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915653/
https://www.ncbi.nlm.nih.gov/pubmed/20721296
http://dx.doi.org/10.1155/2009/362482