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Milk Products Containing Bioactive Tripeptides Have an Antihypertensive Effect in Double Transgenic Rats (dTGR) Harbouring Human Renin and Human Angiotensinogen Genes

Tripeptides isoleucyl-prolyl-proline (IPP) and valyl-prolyl-proline (VPP) act as ACE inhibitors in vitro. Double transgenic rats (dTGR) harbouring human renin and human angiotensinogen genes develop malignant hypertension due to increased angiotensin II formation. The present study was aimed to eval...

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Detalles Bibliográficos
Autores principales: Jauhiainen, Tiina, Pilvi, Taru, Cheng, Zhong Jian, Kautiainen, Hannu, Müller, Dominik N., Vapaatalo, Heikki, Korpela, Riitta, Mervaala, Eero
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915664/
https://www.ncbi.nlm.nih.gov/pubmed/20721338
http://dx.doi.org/10.1155/2010/287030