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Foot-and-Mouth Disease Virus 2C Is a Hexameric AAA+ Protein with a Coordinated ATP Hydrolysis Mechanism

Foot-and-mouth disease virus (FMDV), a positive sense, single-stranded RNA virus, causes a highly contagious disease in cloven-hoofed livestock. Like other picornaviruses, FMDV has a conserved 2C protein assigned to the superfamily 3 helicases a group of AAA+ ATPases that has a predicted N-terminal...

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Detalles Bibliográficos
Autores principales: Sweeney, Trevor R., Cisnetto, Valentina, Bose, Daniel, Bailey, Matthew, Wilson, Jon R., Zhang, Xiaodong, Belsham, Graham J., Curry, Stephen
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915670/
https://www.ncbi.nlm.nih.gov/pubmed/20507978
http://dx.doi.org/10.1074/jbc.M110.129940