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CC2D1A, a DM14 and C2 Domain Protein, Activates NF-κB through the Canonical Pathway

CC2D1A is an evolutionarily conserved protein that contains four DM14 domains at the N terminus and a C2 domain at the C terminus. Loss-of-function mutations in CC2D1A have been linked to mental retardation in human, but the biochemical function of this protein is largely unknown. Here, we show that...

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Detalles Bibliográficos
Autores principales: Zhao, Meng, Li, Xiao-Dong, Chen, Zhijian
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915672/
https://www.ncbi.nlm.nih.gov/pubmed/20529849
http://dx.doi.org/10.1074/jbc.M109.100057