DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences

DNA targeting drugs represent a large proportion of the actual anticancer drug pharmacopeia, both in terms of drug brands and prescription volumes. Small DNA-interacting molecules share the ability of certain proteins to change the DNA helix's overall organization and geometrical orientation vi...

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Detalles Bibliográficos
Autores principales: Lenglet, Gaëlle, David-Cordonnier, Marie-Hélène
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915751/
https://www.ncbi.nlm.nih.gov/pubmed/20725618
http://dx.doi.org/10.4061/2010/290935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915751/
https://www.ncbi.nlm.nih.gov/pubmed/20725618
http://dx.doi.org/10.4061/2010/290935

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