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DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences
DNA targeting drugs represent a large proportion of the actual anticancer drug pharmacopeia, both in terms of drug brands and prescription volumes. Small DNA-interacting molecules share the ability of certain proteins to change the DNA helix's overall organization and geometrical orientation vi...
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| Formato: | Texto |
| Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915751/ https://www.ncbi.nlm.nih.gov/pubmed/20725618 http://dx.doi.org/10.4061/2010/290935 |