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Structure and Stability of a Dimeric G-Quadruplex Formed by Cyclic Oligonucleotides

We have studied the structure and stability of the cyclic dodecamer d<pGGGTTAGGGTTA>, containing two copies of the human telomeric repeat. In the presence of sodium, NMR data are consistent with a dimeric structure of the molecule in which two cycles self-associate forming a quadruplex with th...

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Detalles Bibliográficos
Autores principales: Casals, Joan, Viladoms, Júlia, Pedroso, Enrique, González, Carlos
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915814/
https://www.ncbi.nlm.nih.gov/pubmed/20725624
http://dx.doi.org/10.4061/2010/468017