Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers

The synthesis of oligomers containing two or three acridine units linked through 2-aminoethylglycine using solid-phase methodology is described. Subsequent studies on cell viability showed that these compounds are not cytotoxic. Binding to several DNA structures was studied by competitive dialysis,...

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Detalles Bibliográficos
Autores principales: Ferreira, Rubén, Aviñó, Anna, Pérez-Tomás, Ricardo, Gargallo, Raimundo, Eritja, Ramon
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915818/
https://www.ncbi.nlm.nih.gov/pubmed/20725626
http://dx.doi.org/10.4061/2010/489060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915818/
https://www.ncbi.nlm.nih.gov/pubmed/20725626
http://dx.doi.org/10.4061/2010/489060

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