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Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
The synthesis of oligomers containing two or three acridine units linked through 2-aminoethylglycine using solid-phase methodology is described. Subsequent studies on cell viability showed that these compounds are not cytotoxic. Binding to several DNA structures was studied by competitive dialysis,...
Autores principales: | Ferreira, Rubén, Aviñó, Anna, Pérez-Tomás, Ricardo, Gargallo, Raimundo, Eritja, Ramon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915818/ https://www.ncbi.nlm.nih.gov/pubmed/20725626 http://dx.doi.org/10.4061/2010/489060 |
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