Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens

Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We designed TFO sequences with DNA and 2′-O-meth...

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Detalles Bibliográficos
Autores principales: Krishnan, Rajagopal, Oh, Dennis H.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915845/
https://www.ncbi.nlm.nih.gov/pubmed/20725628
http://dx.doi.org/10.4061/2010/523498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915845/
https://www.ncbi.nlm.nih.gov/pubmed/20725628
http://dx.doi.org/10.4061/2010/523498

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