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Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens
Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We designed TFO sequences with DNA and 2′-O-meth...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915845/ https://www.ncbi.nlm.nih.gov/pubmed/20725628 http://dx.doi.org/10.4061/2010/523498 |