“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

Macrocyclic scaffolds are particularly attractive for designing selective G-quadruplex ligands essentially because, on one hand, they show a poor affinity for the “standard” B-DNA conformation and, on the other hand, they fit nicely with the external G-quartets of quadruplexes. Stimulated by the pio...

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Detalles Bibliográficos
Autores principales: Monchaud, David, Granzhan, Anton, Saettel, Nicolas, Guédin, Aurore, Mergny, Jean-Louis, Teulade-Fichou, Marie-Paule
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915875/
https://www.ncbi.nlm.nih.gov/pubmed/20725629
http://dx.doi.org/10.4061/2010/525862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915875/
https://www.ncbi.nlm.nih.gov/pubmed/20725629
http://dx.doi.org/10.4061/2010/525862

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