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Characterization of Substrate Preference for Slc1p and Cst26p in Saccharomyces cerevisiae Using Lipidomic Approaches and an LPAAT Activity Assay

BACKGROUND: Phosphatidic acid (PA) is a key regulated intermediate and precursor for de novo biosynthesis of all glycerophospholipids. PA can be synthesized through the acylation of lysophosphatidic acid (LPA) by 1-acyl-3-phosphate acyltransferase (also called lysophosphatidic acid acyltransferase,...

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Detalles Bibliográficos
Autores principales: Shui, Guanghou, Guan, Xue Li, Gopalakrishnan, Pradeep, Xue, Yangkui, Goh, Joyce Sze Yuin, Yang, Hongyuan, Wenk, Markus R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915916/
https://www.ncbi.nlm.nih.gov/pubmed/20694142
http://dx.doi.org/10.1371/journal.pone.0011956