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Damage of Streptococcus mutans biofilms by carolacton, a secondary metabolite from the myxobacterium Sorangium cellulosum

BACKGROUND: Streptococcus mutans is a major pathogen in human dental caries. One of its important virulence properties is the ability to form biofilms (dental plaque) on tooth surfaces. Eradication of such biofilms is extremely difficult. We therefore screened a library of secondary metabolites from...

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Detalles Bibliográficos
Autores principales: Kunze, Brigitte, Reck, Michael, Dötsch, Andreas, Lemme, André, Schummer, Dietmar, Irschik, Herbert, Steinmetz, Heinrich, Wagner-Döbler, Irene
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915981/
https://www.ncbi.nlm.nih.gov/pubmed/20659313
http://dx.doi.org/10.1186/1471-2180-10-199