Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity

BACKGROUND: HER2 gene copy status, and concomitant administration of trastuzumab (Herceptin), remains one of the best examples of targeted cancer therapy based on understanding the genomic etiology of disease. However, newly diagnosed breast cancer cases with equivocal HER2 results present a challen...

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Detalles Bibliográficos
Autores principales: Gunn, Shelly, Yeh, I-Tien, Lytvak, Irina, Tirtorahardjo, Budi, Dzidic, Natasha, Zadeh, Soheila, Kim, Jaeweon, McCaskill, Chris, Lim, Lony, Gorre, Mercedes, Mohammed, Mansoor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915985/
https://www.ncbi.nlm.nih.gov/pubmed/20667129
http://dx.doi.org/10.1186/1471-2407-10-396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915985/
https://www.ncbi.nlm.nih.gov/pubmed/20667129
http://dx.doi.org/10.1186/1471-2407-10-396

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